• Methods Mol. Biol. · Jan 2016

    Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases.

    • Melania Spadaro and Edgar Meinl.
    • Institute of Clinical Neuroimmunology, Medical Campus Grosshadern, Ludwig Maximilian University, Marchioninistr. 15, 81377, Munich, Germany.
    • Methods Mol. Biol. 2016 Jan 1; 1304: 99-104.

    AbstractAutoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with different inflammatory demyelinating diseases of the central nervous system, such as childhood multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), and neuromyelitis optica spectrum disorders (NMOSD). We describe here in detail a sensitive cell-based assay that allows the identification of autoantibodies against MOG in serum.

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