• Nutrition · Mar 2020

    Biochemical profile, eating habits, and telomere length among Brazilian children and adolescents.

    • Pâmela Ferreira Todendi, J Alfredo Martínez, Cézane Priscila Reuter, William Latosinski Matos, FrankeSilvia Isabel RechSIRGraduate Program in Health Promotion, University of Santa Cruz do Sul, Santa Cruz do Sul/RS, Brazil., Cristina Razquin, Fermín Ignacio Milagro, Vivian Francília Silva Kahl, Marilu Fiegenbaum, and Andréia Rosane de Moura Valim.
    • Graduate Program in Pathology, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
    • Nutrition. 2020 Mar 1; 71: 110645.

    ObjectivesLifestyle, obesity, and eating habits are emerging as determinants for the instability of telomeres. The increase in childhood and adolescent obesity and the association of biochemical profiles and dietary components with telomere length (TL) makes it an important issue in nutritional research. The aim of the present study was to investigate TL and its association with ethnic background, adiposity, clinical and biochemical parameters, and dietary patterns among Brazilian children and adolescents.MethodsA cross-sectional study encompassing 981 children and adolescents between 7 and 17 y of age was performed. Dietary intake habits, anthropometry, and clinical data were collected. TL analysis was performed by quantitative polymerase chain reaction.ResultsChildren presented significantly longer TL than adolescents (P = 0.046). Participants who self-declared as black, mulatto, or brown (P < 0.001) also showed longer TL than those who were white. Regarding biochemical parameters, individuals with altered glucose levels had shorter TL than normoglycemic participants in the total sample (P = 0.014). Such difference remained statistically significant in adolescents (P = 0.019). Participants who reported eating fruits and vegetables regularly had longer TL than those who did not (P < 0.001).ConclusionThe results suggested that both biochemical parameters and the intake of antioxidant-rich food, such as fruits and vegetables, are associated with the stability of telomere biology among young Brazilians.Copyright © 2019 Elsevier Inc. All rights reserved.

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