• Tomasz Krauze, Katarzyna Cebrowska, Agata Schneider, Adam Szczepanik, Agnieszka Banaszak, Agnieszka Rutkowska, Marek Balinski, Przemysław Guzik, and Andrzej Wykrętowicz.
• Department of Cardiology‑Intensive Therapy, Poznan University of Medical Sciences, Poznań, Poland
• Pol. Arch. Med. Wewn. 2020 Jun 6; 130 (6): 512-519.

IntroductionGrip strength and blood pressure are strongly interrelated. Blood pressure is an essential component of arterial load, which modulates cardiac output.ObjectivesWe aimed to asses the correlation between grip strength and both steady and pulsatile components of arterial load in patients with acute myocardial infarction.Patients And MethodsWe included 295 participants (mean age, 63 years) with acute myocardial infarction. The following data were assessed: grip strength, echocardiography, local arterial stiffness, arterial tonometry, continuous arterial pulse, and beat‑to‑beat wave.ResultsIn univariable analyses, grip strength correlated with arterial stiffness (pulse wave velocity), ventricular-arterial coupling, and measures of pulsatile arterial load: aortic characteristic impedance (Zao), total arterial compliance (TAC), and central fractional arterial pulse pressure (cFPP). In a multivariable model including age, grip strength, body mass index, systolic blood pressure, sex, and descriptors of pulsatile load, the following remained associated with grip strength: Zao (R2 for the model = 0.58; P <0.001), TAC (R2 = 0.23 for the model; P <0.001), and cFPP (R2 for the model = 0.2; P <0.001). In the second model that included sex, only Zao remained associated with grip strength (R2 for the model = 0.67). Comparisons between men and women of the adjusted mean value demonstrated that Zao and cFPP were considerably higher (P <0.001 and P = 0.02, respectively) and TAC was lower in women (P <0.001).ConclusionsIn a cohort of patients with acute myocardial infarction, grip strength correlated independently and significantly with descriptors of the pulsatile arterial load. The role of sex in these interrelations needs further study.

9 keywords...

hide…