African health sciences
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African health sciences · Dec 2018
Randomized Controlled TrialWalking as a feasible means of effecting positive changes in BMI, waist, and blood pressure in black South African women.
In the context of a growing obesity pandemic in sub-Saharan African countries little is known on how to address the problem /disease in the region. ⋯ Our data demonstrates that positive changes in BMI, waist, and BP were observed in the intervention group, indicating the potential scalability of the intervention.
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African health sciences · Dec 2018
Dose related effects of oral clonidine pre-medication on bupivacaine spinal anaesthesia.
The duration of action of sub-arachnoid block is short, and one of the ways to overcome this is the use of oral clonidine. ⋯ Oral clonidine produces better clinical effects on the onset and duration of Bupivacaine spinal anaesthesia.
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African health sciences · Dec 2018
Audit of insulin prescription patterns and associated burden among diabetics in a tertiary health institution in Nigeria.
Insulin is one of the most important anti-diabetic agents in the management of diabetes even among type 2 diabetic. ⋯ The insulin adherence among diabetics in this study was high. Non-availability of insulin, insulin injection pain and being tired of continual insulin usage were some of the reasons for non-adherent to insulin usage.
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African health sciences · Dec 2018
Clinical TrialExercise capacity and muscle fatiguability alterations following a progressive maximal exercise of lower extremities in children with cystic fibrosis.
Impairment of peripheral skeletal muscle function is a common phenomenon in patients with cystic fibrosis (CF) in addition to great clinical connotations, such as lack of exercise tolerance and decrease of health-related quality of life. There is very limited data on the effects of maximal exercise on muscle fatiguability and exercise capacity in children with cystic fibrosis. ⋯ This study indicates that progressive maximal exercise doesn't affect muscle fatiguability, muscle cross-section area, and maximal voluntary contraction in CF children with moderate respiratory diseases but includes lower exercise capacity. CF children and healthy age matched children have similar responses to maximal exercise in muscle fatiguability, muscle cross-section area, and maximal voluntary contractions but lower exercise capacity in the CF group.
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African health sciences · Dec 2018
Interferon-γ receptor-1 gene promoter polymorphisms and susceptibility for brucellosis in Makkah region.
Genetic polymorphisms that affect the production levels of certain cytokines and/or their receptors may determine the risk, severity or protection in some infectious diseases like brucellosis. ⋯ Both tested polymorphisms, IFN-γ R1 - 56 C>T and IFN-γ R1 -611 A>G polymorphism had no role in genetic susceptibility to human brucellosis in the study population. The PCR-CTPP can be used for genotyping IFN-γ R1 - 611 A > G polymorphism and other types of mutation.