African health sciences
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African health sciences · Dec 2018
Inhibition of cell proliferation, migration and colony formation of LS174T Cells by carbonic anhydrase inhibitor.
Metastasis is the leading cause of cancer deaths. Migration of tumor cells is an important stage in metastasis. Therefore, recent studies have focused on clarifying migration and migration-dependent cell functions such as angiogenesis, wound healing, and invasion. ⋯ Acetazolamide was observed to significantly inhibit the cell viability, colony forming capacity, and migration ability in the culture medium of LS174T cells. This inhibitor effect of acetazolamide was observed to be dependent on the concentration in medium.
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African health sciences · Dec 2018
Diagnostic performance of several biomarkers for identification of cases of non-communicable diseases among Central Africans.
This study determined the diagnostic performance of new biomarkers for a composite diagnosis of non-communicable diseases (NCDs) among Central Africans. ⋯ Serum Se, NO, calcium, TSH and daily salt intake had high diagnostic performance as biomarkers for identification of patients with concurrent NCDs in the study population.
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African health sciences · Dec 2018
Low birth weight and associated factors among singleton neonates born at Felege Hiwot referral hospital, North West Ethiopia.
Low birth weight is one of the public health problems in the globe and it is an indicator of the health of the newborn survival and the mother's nutrition and health status. This study was aimed to determine the prevalence of low birth weight and its associated factors among mothers who gave birth at Bahir Dar Felege Hiwot referral hospital. ⋯ The prevalence of low birth weight was in line with WHO estimate for sub-Saharan Africa. Nutritional counseling and early detection and management of pregnancy induced hypertension is recommended.
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African health sciences · Dec 2018
Resistance status to deltamethrin pyrethroid of Culex pipiens pipiens (Diptera: Culicidae) collected from three districts of Tunisia.
The aim of the present study was to determine the susceptibility status of Culex pipiens pipiens populations against deltamehtrin insecticide. ⋯ The results obtained from this study should be considered in the current control programs to combat mosquitoes in Tunisia.
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African health sciences · Dec 2018
Cytomegalovirus infection among Human Immunodeficiency Virus (HIV) infected individuals on highly active anti-retroviral therapy in North-Central Nigeria.
Cytomegalovirus (CMV) infection is common among HIV-infected individuals. Its contribution to morbidity and mortality became more apparent following introduction of highly active anti-retroviral therapy (HAART) which improved survival among HIV-infected individuals. ⋯ This study has demonstrated high level of latent and active CMV infection among HAART recipients in Ilorin and highlighted the need for incorporation of anti-herpes drugs in the treatment regimen.