African health sciences
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African health sciences · Dec 2018
Investigating the influence of contextual factors in the coordination of chronic mental illness care in a district health system.
The global shift from institution-based to community-based care for chronic mental illness (CMI) care resulted in the de-institutionalization of clients with CMI. However, health systems which have been originally designed for acute hospital-based care do not seem to be appropriately transformed to manage CMI care at a community level. ⋯ The study concluded that the eThekwini District health facility settings were not adequately equipped to respond to care coordination demands for chronic mental illness care.
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African health sciences · Dec 2018
Ethnobotanical study of curative plants used by traditional healers to treat rhinitis in the Limpopo Province, South Africa.
Studies focusing on plants used medicinally to heal and manage rhinitis are very scarce in Africa and elsewhere. ⋯ This study is the first to document plants used traditionally to treat rhinitis in Africa. Therefore, it provides a baseline data on the plants used to heal rhinitis in the Limpopo Province. Finding of this study can be used as apedestal for further investigation in to effective plant-based anti-rhinitis drugs.
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African health sciences · Dec 2018
The immunomodulatory peptide bursopentin (BP5) enhances proliferation and induces sIgM expression in DT40 cells.
In the recent past, many studies have been focused on extracts of BF and multiple biologically active factors and their effects on humoral immune system in chickens and birds. However, the mechanism of those immunomodulatory peptides on the B lineage cells proliferation and antibody production in chicken is fairly unknown. DT40 cell line, an avian leucosis virus-induced chicken pre-B cell line, expresses immunoglobulin M (IgM) isotype B cell reporter in the plasma membrane. There are many evidences suggesting that DT40 cells are best characterized as a bursal stem cell line. Because of the unique characteristics of DT40 cell line, it has been widely used to observe biological processes of pre-B lymphocyte cell within living cells. ⋯ Theses findings showed the immuno-activity effect of BP5 on B lymphocyte and indicated that BP5 treatment regulated eight signaling pathways, in which Toll-like signaling pathway was the most significant enrichment pathway.
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African health sciences · Dec 2018
Meta AnalysisWomen's attitude and reasons toward justifying domestic violence in Ethiopia: a systematic review and meta-analysis.
Domestic violence (DV) is a global public problem that touches all levels of society and socio-economic status. Identifying women's attitudes towards domestic violence is an important first step in the prevention and control of its consequence. Thus, this systematic review and meta-analysis aimed: (i) to synthesize women's reasons for justifying domestic violence and (ii) to determine the pooled prevalence of women's attitude towards domestic violence in Ethiopia. ⋯ More than half of women accept domestic violence. Authors' suggest strengthening of women's awareness toward norms that justify wife beating.