Chinese medical journal
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Chinese medical journal · Jan 2020
Meta AnalysisAssessment of prophylactic antibiotics administration for acute pancreatitis: a meta-analysis of randomized controlled trials.
Recent evidence has shown that prophylactic antibiotic treatment in patients with acute pancreatitis is not associated with a significant decrease in mortality or morbidity. The use and efficacy of prophylactic antibiotic treatment in acute pancreatitis remain controversial. This meta-analysis was conducted to assess whether antibiotic prophylaxis is beneficial in patients with acute pancreatitis. ⋯ Prophylactic antibiotics can reduce the incidence of non-pancreatic infection in patients with AP.
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Chinese medical journal · Jan 2020
Meta AnalysisEfficacy and safety of chimeric antigen receptor-T cells in the treatment of B cell lymphoma: a systematic review and meta-analysis.
Conventional treatment has limited efficacy in relapsed/refractory B-cell lymphoma. Since chimeric antigen receptor T-cell (CAR-T) technology has shown high safety and results in high remission rates, we investigated its efficacy and safety in B-cell lymphoma treatment and analyzed potential affecting factors to provide evidence for therapeutic strategies and applications. ⋯ CAR-T cell treatment is safe for clinical application; however, toxicity effects should be monitored.