Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Jul 2021
Neurodevelopmental outcome of very preterm infants with gastrointestinal tract perforations does not differ compared to controls.
To evaluate gastrointestinal tract (GIT) perforations in very low birth weight infants and the effects on neurodevelopmental outcome. ⋯ Despite increased morbidities preterm infants with GIT perforation did not have a higher mortality rate and groups did not differ regarding neurodevelopmental outcome at the corrected for prematurity age of 2 years.
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Wien. Klin. Wochenschr. · Jul 2021
A data-driven framework for introducing predictive analytics into expanded program on immunization in Pakistan.
Pakistan has a nationwide expanded program on immunization (EPI), yet vaccination coverage in Pakistan is quite low. Recently, an analytical model has been proposed to improve the coverage by identifying children who are most likely to miss any of the vaccines included in the immunization schedule, known as defaulters; however, a number of limitations remain unresolved in the previously proposed model. Firstly, it only classified children into two stages: defaulters and non-defaulters, considering all children at high risk of defaulting even if only one dose is missed. Secondly, there was no categorisation of high and low coverage areas for prioritised vaccination. The aim of this study was to propose a prediction framework for the accurate identification of defaulters. ⋯ The proposed framework in this study is a step forward towards a data-driven approach and provides a set of machine learning techniques to utilise predictive analytics. Hence, this can reinforce immunization programs by expediting targeted action to reduce drop-outs.
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Wien. Klin. Wochenschr. · Jul 2021
Noninvasive ventilation for respiratory distress syndrome is a potential risk factor for retinopathy of prematurity : Single Slovenian tertiary center study.
Retinopathy of prematurity (nROP) among extremely low gestational age newborns (ELGAN) in Slovenia has increased in recent years. At the same time mortality has further decreased and less invasive approaches for treatment of respiratory distress syndrome have been established. ⋯ The results showed that the duration of noninvasive ventilation is a potential risk factor for ROP. Controlling for known risk factors for ROP and then adjusting for gestational age, number of transfusions and fraction of inspired oxygen (FiO2), the odds of ROP were 1.22 times greater (95% confidence interval, CI 1.01-1.48) with every additional week of noninvasive ventilation (p = 0.03).
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Wien. Klin. Wochenschr. · Jul 2021
Complete hemogram: simple and cost-effective in staging and predicting outcome in acute pancreatitis.
An important goal in management of acute pancreatitis (AP) is early prediction and recognition of disease severity. Various predictive scoring systems are in clinical use with their own limitations and there is always a quest for simple, practical, quantifiable, dynamic and readily available markers for predicting disease severity and outcome. Complete hemogram is routinely ordered in all patients with AP. In recent years red cell distribution width (RDW), neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet lymphocyte ratio (PLR) have been found to be independent predictors of prognosis in various benign and malignant conditions. This prospective study evaluated complete hemogram based markers in AP. ⋯ Hemogram based markers are simple, objective, dynamic and readily available. They can be considered in addition to conventional multifactorial scoring systems for prediction of outcome and prognosis of AP.
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Wien. Klin. Wochenschr. · Jul 2021
The role of quantitative HBsAg in patients with HBV DNA between 2000-20,000 IU/ml.
We aimed to determine the contribution of quantitative HBsAg in differentiating chronic infections from chronic hepatitis in HBeAg negative patients with HBV DNA 2000-20,000 IU/ml. ⋯ Our study suggests that the quantitative HBsAg ≤ 1000 IU/ml limit value might be used for the diagnosis of chronic infection not only in HBV DNA ≤ 2000 IU/ml but also in patients with HBV DNA between 2000-20,000 IU/ml. In addition, antiviral treatment could be considered in patients with quantitative HBsAg > 20,000 IU/ml and HBV DNA > 2000 IU/ml without further examinations such as liver biopsy.