European journal of clinical investigation
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Eur. J. Clin. Invest. · Feb 2021
Review Meta AnalysisInhaled corticosteroids and risk of lung cancer: A systematic review and meta-analysis.
Current studies investigating the association between inhaled corticosteroid (ICS) use and risk of lung cancer have yielded inconsistent findings. The aim of this systematic review and meta-analysis was to pool all currently available data to estimate this association. ⋯ The present study suggested that ICS use was associated with decreased risk of lung cancer. However, our findings should be interpreted with caution because most original studies were judged to be at high risk of immortal time bias.
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Eur. J. Clin. Invest. · Feb 2021
Meta AnalysisEffects of antidiabetic drugs on psoriasis: A meta-analysis.
Psoriasis, a chronic inflammatory skin disease, poses an elevated risk of developing diabetes mellitus. ⋯ The current evidence demonstrates therapeutic efficacy of pioglitazone, which may be a treatment option in patients with psoriasis and diabetes mellitus.
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Eur. J. Clin. Invest. · Feb 2021
Review Meta AnalysisMicroRNA-223 in Gastrointestinal Cancers: A Systematic Review and Diagnostic Meta-Analysis.
Several studies have been conducted on the diagnostic role of miR-223 in cancers related to the digestive system. However, the diagnostic role of this microRNA in gastrointestinal (GI) cancers has not been fully elucidated. This meta-analysis aimed to accurately assess the diagnostic role of circulating miR-223 in GI cancers. ⋯ Our meta-analysis showed the value of circulating miR-223 levels in the early diagnosis of diverse digestive system carcinomas.