Medicine
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Observational Study
Exploration in association between vitamin D, sleep quality, and osteoarthritis: A modeling study.
Previous studies on the relationship between vitamin D, sleep quality, and osteoarthritis (OA) have been controversial and the aim of this study is to analyze the association. In this study, relevant data from 2 survey cycles (2009-2010 with 2011-2012) are downloaded from the CDC's NHANES project to analyze the relationship between vitamin D, sleep quality, and osteoarthritis, as well as other related risk factors. The analysis of statistics in this study is performed using t-tests and chi-square tests, modeling is performed using logistic regression based on NHANES weights, and other risk factors are analyzed using forest plots. ⋯ This study is based on a larger sample and a stepwise logistic regression of multiple covariates. We concluded that vitamin D may not influence OA. However other risk factors for OA are confirmed, including advanced age, female and high BMI, especially bad sleep quality.
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Oxidative stress is an essential contributor to the progression of chronic obstructive pulmonary disease (COPD). A systematic assessment of diet patterns and lifestyle with the oxidative balance score (OBS) to reflect oxidative stress levels will help predict the risk of COPD. This study conducted a cross-sectional analysis to assess the link between OBS and COPD. 5162 participants were collected from 2013 to 2018 from the National Health and Nutrition Examination Survey (NHANES). ⋯ The smoothed curve fitting supported the negative association between OBS and COPD. Subgroup analyses revealed that the protective effect of OBS was notably pronounced among the non-hypertensive and non-diabetic populations. These findings suggest a negative link between OBS and COPD, underscoring the importance of antioxidant-rich diets and lifestyles in preventing COPD.
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Kneeling and half-kneeling training are common positions used in physical therapy. however, research on lower extremity muscle activity is lacking compared to the ergonomic aspects and trunk muscle activity. The purpose of this study is to investigate the effects on lower extremity muscle activity during squats in kneeling and half-kneeling positions. The study was designed as a cross-sectional study with a single group of healthy adults. ⋯ In the HKP, there were statistically significant differences between the ascent and descent phases of the RF, GMax, and GMed (P < .05). The results of this study indicate that squats in the HKP (especially during the ascent phase) require the highest muscle activity, whereas squats in the KP (especially during the descent phase) can be performed with the lowest muscle activity. It can be concluded that these findings could serve as selective indicators for squat exercises and in enhancing postural control, muscle strength, and lower extremity stabilization.
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Observational Study
Early prediction of intraoperative hypothermia in patients undergoing gynecological laparoscopic surgery: A retrospective cohort study.
Intraoperative hypothermia is one of the most common adverse events related to surgery, and clinical practice has been severely underestimated. In view of this, this study aims to build a practical intraoperative hypothermia prediction model for clinical decision-making assistance. We retrospectively collected clinical data of patients who underwent gynecological laparoscopic surgery from June 2018 to May 2023, and constructed a multimodal algorithm prediction model based on this data. ⋯ The prediction efficiency of other prediction models is 0.783 and 0.821, with a 95% confidence interval of 0.725 to 0.841 and 0.763 to 0.879, respectively. The intraoperative hypothermia prediction model based on machine learning has satisfactory predictive performance, especially in random forests. This interpretable prediction model helps doctors evaluate the risk of intraoperative hypothermia, optimize clinical decision-making, and improve patient prognosis.
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Spinal cord injury has a significant impact on patients' physical and mental health, with cell death playing a key role in the pathology. ⋯ Publications in this field have grown rapidly in the past 2 decades and are expected to keep increasing. Current hot topics include mesenchymal stem cells, apoptosis, autophagy, and ferroptosis. Future research will focus on extracellular vesicle-mediated mesenchymal stem cells, autophagy, inflammasome-mediated cell pyroptosis, and glial scar formation.