Medicine
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We evaluated the relationship between sleep factors and tinnitus risk using data from the US National Health and Nutrition Examination Survey (2007-2012), focusing on adults aged 20 to 80 years. Our analysis included 4354 participants, with sleep patterns categorized as healthy, intermediate, or poor. ⋯ Additionally, sleep disturbances were significantly correlated with tinnitus (OR: 1.52), with the strongest association occurring in individuals with poor sleep patterns (OR: 1.71). The results of the weighted logistic regression analysis underscored these findings.
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Primary diffuse large B-cell lymphoma of the bone (PB-DLBCL) is an extremely rare type of extra-nodal lymphoma. The clinical characteristics, management, and survival outcomes of adult PB-DLBCL patients remain poorly defined. To explore the clinical manifestations, staging, therapeutic options, prognostic factors and outcomes of adult patients with PB-DLBCL and to create a model to predict survival outcomes. ⋯ For OS, age, Ann Arbor stage, primary site and therapy were confirmed as final factors to develop the nomogram in adult PB-DLBCL patients, whereas for DSS, Age, marital status, Ann Arbor stage, number of bone lesions, therapy and year of diagnosis were confirmed as final factors in developing the nomogram. The nomograms demonstrated good accuracy and clinical utility. Established nomograms can accurately predict the survival of patients with PB-DLBCL and help clinicians optimize treatment.
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Increasing evidence indicates a significant correlation between gut microbiota (GM) and susceptibility to chronic kidney disease (CKD). However, causal relationship presence remains uncertain. Mendelian randomization (MR) was applied to evaluate potential causal relation from GM to CKD. ⋯ According to the investigation, MR method was employed to delve into reciprocal causal connection from GM to CKD. Our findings identified 15 types of GM causally linked to CKD, as well as CKD demonstrating causal associations with 3 types of GM. Further exploration of these associated GM types is hopeful to raise novel insights, for CKD preventing and early monitoring.
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Schizophrenia and magnetic resonance imaging research: A scientometric analysis during 2014 to 2023.
Recently, magnetic resonance imaging (MRI) has emerged as a leading technique for investigating schizophrenia (SZ) pathological mechanisms, prompting an increase in related studies. This study aims to examine the field's research status and trends via bibliometric analysis. ⋯ This study offers an overview of the research status and trends of publications on SZ and MRI, aiming to inspire future research directions.
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Observational Study
Correlation of exercise blood pressure levels with concomitant cardiovascular disease.
Hypertension is a fatal but preventable risk factor for cardiovascular disease and an important cause of death from cardiovascular disease. Exercise training has a definite clinical effect on blood pressure control. However, inappropriate exercise is ineffective and may also cause disease. ⋯ At the same time, the smoking rate and glycohemoglobin level of the patients with abnormal exercise blood pressure were significantly increased (all P < .05), but there was no statistically significant difference in age, sex, body mass index, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and other indicators between the 2 groups (all P > .05). Patients with abnormal exercise blood pressure response have a higher prevalence of hypertension and coronary heart disease. Exercise blood pressure level may be an important factor affecting patients' cardiovascular prognosis.