Clinical neurology and neurosurgery
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Clin Neurol Neurosurg · Apr 2003
Clinical TrialIs mannitol safe for patients with intracerebral hemorrhages? Renal considerations.
Mannitol, a drug widely used to decrease intracranial pressure, can cause renal failure. The goal of this study is to determine the renal safety of mannitol therapy in patients with intraparenchymal hemorrhages. ⋯ Our study points out safety of mannitol therapy under control of osmolality, although control of urea and creatinine concentrations in special group of patients (persons with history of renal failure or diabetes) should be considered.