Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine
-
To improve the robustness of arterial spin-labeled measured perfusion using a novel Cartesian acquisition with spiral profile reordering (CASPR) 3D turbo spin echo (TSE) in the brain and kidneys. ⋯ The CASPR view ordering with 3D TSE achieves robust arterial spin-labeled perfusion in the brain and kidneys because of the sampling of the center of k-space at the beginning of each echo train.
-
CEST is commonly used to probe the effects of chemical exchange. Although R1ρ asymmetry quantification has also been described as a promising option for detecting the effects of chemical exchanges, the existing acquisition approaches are highly susceptible to B1 RF and B0 field inhomogeneities. To address this problem, we report a new R1ρ asymmetry imaging approach, AC-iTIP, which is based on the previously reported techniques of irradiation with toggling inversion preparation (iTIP) and adiabatic continuous wave constant amplitude spin-lock RF pulses (ACCSL). We also derived the optimal spin-lock RF pulse B1 amplitude that yielded the greatest R1ρ asymmetry. ⋯ The AC-iTIP approach could probe the chemical exchange effect more robustly than the existing R1ρ asymmetry acquisition approaches. Therefore, AC-iTIP is a promising technique for metabolite imaging based on the chemical exchange effect.