Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
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Comparative Study Clinical Trial Controlled Clinical Trial
Automatic generation of a plan optimization volume for tangential field breast cancer radiation therapy.
Dose homogeneity is one of the objectives during computer planning of postoperative radiotherapy of the conserved breast. For three-dimensional (3-D) optimization of the dose distribution using serial CT scan images, suitable volumes have to be delineated. The purpose of this study was to develop a computer-generated delineation of a plan optimization volume (POV) and an irradiated volume (IV) and to automate their use in a fast dose homogeneity optimization engine. ⋯ This automated planning method is capable of replacing the contouring of the clinical target volume as well as the trial-and-error procedure of assigning weights of wedged and unwedged beams by an experienced planner.
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Comparative Study Clinical Trial Controlled Clinical Trial
Evaluation of HDR interstitial breast implants planned by conventional and optimized CT-based dosimetry systems with respect to dose homogeneity and conformality.
Recently, the use of brachytherapy for partial breast irradiation has increased significantly. The aim of this study was to make dosimetric comparisons between conventional (CONV) and CT-based optimized dosimetry systems applied to breast implants. ⋯ With CT-based optimized dose planning the target coverage can be significantly increased compared to the conventional dosimetry systems, but the target dose distribution will be more inhomogeneous. To improve the quality of brachytherapy implants, the image-based three-dimensional information should be used not only for dose plan evaluation, but also previously, for planning the geometry of the catheter positions and performing the insertions.