Nutrition
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The beneficial influence of a vegetarian diet in reducing the risk for metabolic syndrome has been demonstrated. However, adiponectin production and secretion are scarcely studied in vegetarians, despite their important role in recovering metabolic homeostasis by reducing visceral obesity, inflammation, and insulin resistance. The aim of this study was to evaluate the effect of a vegetarian diet on serum adiponectin levels and its association with the established biomarkers of insulin sensitivity and inflammation in healthy, non-obese individuals. ⋯ A vegetarian diet resulted in improved β-cell function. Favorable adiponectin and insulin sensitivity responses in women reveal a distinct effect of diet-to-metabolic homeostasis, indicating an interesting pattern of sexual dimorphism regarding the beneficial metabolic effect of a vegetarian diet.
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Retinol and β-carotene have been reported to be involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, clinical studies are limited. The aim of this study was to investigate the relationship between serum the ratio of β-carotene to retinol (SC/SR) and hepatic steatosis in NAFLD diagnosed by ultrasonography. ⋯ The SC/SR ratio was lower in NAFLD with sex differences, and was associated with the severity of hepatic steatosis and lipid profile. Future studies are needed to expand on these findings.
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This study aimed to analyze the effect of creatine (Cr) supplementation on tumor microenvironment, evaluating the parameters of tumor aggressiveness. ⋯ Cr supplementation in Walker-256 tumor-bearing rats did not induce significant changes in tumor development, and did not interfere with the parameters of tumor aggressiveness, such as the level of cell differentiation and proliferation.
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The aim of this study was to investigate the differences in the quality of nutritional care among Austria, Switzerland, and Turkey. ⋯ The findings of this study indicated that significant differences exist in the prevalence, identification and treatment of malnutrition, and the fulfillment of structural quality indicators. Standards and guidelines need to be developed that can be used by all countries. The severity of the malnutrition situation in hospitals needs further attention in future management policies.
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Obese patients have an increased risk of developing acute myeloid leukemia (AML), which in turn predisposes to malnutrition. Obesity has been associated with improved survival in critically ill patients (obesity paradox), but this effect seems to disappear when adjusting for malnutrition. How obesity and malnutrition interplay to affect mortality in critically ill patients with AML has not been addressed and was the objective of this study. ⋯ Critically ill patients with AML have a high prevalence of malnutrition and obesity, which are sometimes associated. Malnutrition, but not obesity, was associated with hospital mortality.