Nutrition
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Randomized Controlled Trial
One week of high-fat overfeeding alters bone metabolism in healthy males: A pilot study.
Short periods of excessive consumption of indulgent high-fat foods are common in Western society, but the effect this has on bone is unknown. The aim of this pilot study was to explore how a 7-d hyperenergetic, high-fat diet affects candidate biomarkers of bone metabolism. ⋯ A 7-d hyperenergetic, high-fat diet reduces a marker of bone formation but does not affect a marker of bone resorption. This pilot study suggested that short periods of excessive energy and fat consumption may detrimentally affect bone health.
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This study aimed to compare the accuracy of four machine-learning (ML) algorithms, using two classification schemes, to predict undernutrition based on individual and household risk factors. ⋯ The random forest algorithm performed best in predicting undernutrition among Filipino elementary schoolchildren, although results could be improved with bootstrap aggregation. The AMDR classification shows potential for targeting feeding beneficiaries. However, local dietary culture should be considered in the development of nutrition interventions. Government use of big-data techniques such as ML must also address underrepresentation in health data collected from and accessible to poor populations or risk further marginalizing them.
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Body-composition analysis using bioelectrical impedance analysis is gradually becoming more widely used in clinical practice. The ratio of extracellular water (ECW) to total body water (TBW) is thought to be related to the prognosis of a variety of diseases. However, its performance in people with advanced cancer deserves further discussion. ⋯ We found that in people with cancer, an ECW/TBW ≥ 0.40 was a risk factor for malnutrition and lower health-related quality of life, and in people with advanced cancer, it was a risk factor for poor prognosis.
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Probiotics and their food sources, prebiotics, are known to have qualities that help with gastrointestinal issues along with overall improvement in health and well-being. Pro- and prebiotics play a key role in neuroimmune processes. Their beneficial effects on health are linked to interactions of the gastrointestinal tract, immune system, and neurologic systems. ⋯ Nutrition has the potential to increase psychological well-being and could be used much as are psychiatric drugs. Probiotics and prebiotics have evolved as promising therapeutic techniques to treat several disease conditions associated with the gastrointestinal tract. The aim of this review was to provide useful information about the use of probiotics and prebiotics in mitigation of various diseases such as COVID-19, congenital heart disease, diarrhea, inflammatory bowel disease, hypertension, genitourinary tract infection, colon cancer, immune system defense, mineral absorption, allergic disorders, and atopic dermatitis.
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Disease-related malnutrition remains a major burden for patients and health care systems. The Medication Pass Nutritional Supplement Program (MEDPass) involves providing patients with oral nutritional supplements (ONS) in unusually small amounts three to four times per day during medication rounds. This systematic review aims to evaluate the impact of MEDPass ONS administration on compliance, total energy and protein intake, food intake, body weight and handgrip strength in hospitalized adults and nursing-home residents. ⋯ We conclude that MEDPass ONS administration increases compliance in hospitalized adults and nursing-home residents. For all other outcomes, robust and well-powered trials are necessary.