Journal of clinical anesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Ketorolac for early postoperative analgesia.
To determine the efficacy and speed of onset of analgesia of a single dose of intravenous (IV) or intramuscular (IM) ketorolac tromethamine following major orthopedic surgery. ⋯ Despite high patient acceptability compared with placebo, the use of ketorolac as the sole analgesic failed to control postoperative pain following major orthopedic surgery. IV administration of ketorolac conferred no advantages over the IM route with regard to efficacy or speed of onset.
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Randomized Controlled Trial Clinical Trial
Epidural scopolamine administration in preventing nausea after epidural morphine.
To determine the effectiveness of epidural scopolamine in preventing nausea and vomiting in patients receiving epidural morphine. ⋯ Epidural scopolamine can be used as an adjunct to epidural morphine in effectively reducing the incidence of postoperative nausea and vomiting.
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Randomized Controlled Trial Clinical Trial
Effect of intrathecal sufentanil on isoflurane requirements during lower abdominal surgery.
To determine the effect of intrathecal sufentanil on volatile anesthetic requirements during lower abdominal surgery. ⋯ Prior administration of intrathecal sufentanil significantly decreases the isoflurane requirement in surgical patients, in addition to its previously demonstrated rapid onset and receptor efficacy.
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Clinical Trial
The effect of epidural blood patch on hearing loss in patients with severe postdural puncture headache.
To determine the immediate effect of epidural blood patch (EBP) on the hearing loss that can accompany postdural puncture headache (PDPH). ⋯ Epidural blood patch improves hearing within one hour in the majority of patients with severe PDPH.
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Randomized Controlled Trial Comparative Study Clinical Trial
Use of analgesics during propofol sedation: a comparison of ketorolac, dezocine, and fentanyl.
To evaluate the comparative efficacy and side effect profile of ketorolac 60 mg, dezocine 6 mg, and fentanyl 100 micrograms when used as analgesic supplements to a propofol infusion during monitored anesthesia care (MAC). ⋯ Compared with ketorolac 60 mg, fentanyl 100 micrograms and dezocine 6 mg produced a greater decrease in the propofol sedation requirement during MAC. However, the use of ketorolac in combination with propofol for MAC was associated with an improved recovery profile.