Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
A randomized, double-blind, dose-response study of ondansetron in the prevention of postoperative nausea and vomiting.
To determine the dose-response relationship of ondansetron in preventing postoperative nausea and vomiting (PONV) in women undergoing elective surgery. ⋯ The recommended dose of ondansetron for PONV prophylaxis in women remains 4 mg.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of recovery after sevoflurane or desflurane in ambulatory anesthesia.
To determine if there is a difference between sevoflurane and desflurane when used as part of a balanced anesthetic technique in terms of time to discharge from an ambulatory surgery unit. ⋯ Recovery indices and psychomotor function are marginally but not significantly better with sevoflurane than desflurane.
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Randomized Controlled Trial Clinical Trial
Laboratory evaluation of single-lumen, dual-orifice combined spinal-epidural needles: effects of bevel orientation and modified technique.
To evaluate the success rate of the spinal needle exiting through the spinal needle orifice in two commonly available single-lumen, dual-orifice combined spinal-epidural (CSE) needle kits, and to study the effects of the epidural needle bevel orientation and the modified insertion technique on its success rate. ⋯ The spinal needle did not always exit through the spinal needle orifice in the CSE kits tested. CSE-Q kits performed better than CSE-S kits. Under the study conditions, the modified technique and the upward orientation of epidural needle bevel significantly improved the success rate of the spinal needle exiting through the appropriate spinal needle orifice.
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Randomized Controlled Trial Clinical Trial
Combined intrathecal fentanyl and neostigmine: therapy for postoperative abdominal hysterectomy pain relief.
To evaluate the analgesic action of spinal neostigmine as part of a multimodal analgesic therapy approach including spinal neostigmine and spinal fentanyl for postoperative pain relief ⋯ The combination of 25 microg neostigmine with 25 microg fentanyl given intrathecally with 15 mg of hyperbaric bupivacaine delayed postoperative pain and lowered the number of rescue analgesics. Because the better quality of analgesia was obtained with an increased (although not statistically significant difference) incidence of untoward side effects, larger samples should be studied before its routine use is recommended.
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To characterize the clinical features that predispose to sinus bradycardia and cardiac arrest during spinal and epidural anesthesia. ⋯ The clinical picture suggests a reflex cause, possibly associated with low right-sided cardiac filling pressure. No common precipitating cause or high-risk patient profile was noted.