Journal of clinical anesthesia
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Randomized Controlled Trial Clinical Trial
Fenoldopam infusion for the treatment of postoperative hypertension.
To examine the safety and efficacy of intravenous fenoldopam as compared to placebo for the treatment of postoperative hypertension. ⋯ Fenoldopam is an effective drug for reducing BP following hypertensive episodes in the postoperative setting. Fenoldopam use is associated with an increase in HR versus placebo.
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Randomized Controlled Trial Clinical Trial
Midazolam pretreatment does not ameliorate myoglobinemia or the clinical side effects of succinylcholine.
To determine whether the levels of serum myoglobin and the occurrence of fasciculations and postoperative symptoms following a single dose of succinylcholine are modified by the prior administration of midazolam. ⋯ Midazolam had no effect on myoglobin level or postoperative symptoms following succinylcholine.
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Randomized Controlled Trial Clinical Trial
The effect of intravenous dextrose infusion on postbypass hyperglycemia in pediatric patients undergoing cardiac operations.
To determine whether elimination of intraoperative dextrose-containing infusions affects post-cardiopulmonary bypass hyperglycemia in pediatric patients. ⋯ Extreme postbypass hyperglycemia can be controlled by eliminating intraoperative dextrose infusions. Hypoglycemia, an unlikely event, can easily be avoided by regular blood sampling, which is facilitated by the routine placement of arterial catheters.
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To estimate the sensitivity and specificity of somatosensory evoked potentials (SSEPs) for predicting new postoperative motor neurologic deficits during intramedullary spinal cord surgery; to establish whether SSEPs more accurately predicted postoperative deficits in position and vibration sense than in strength. ⋯ Intraoperative SSEP changes during intramedullary spinal cord surgery are a sensitive predictor of new postoperative motor deficits, but such changes may not correlate reliably with postoperative deficits in position or vibration sense. In this setting SSEP monitoring serves primarily to reassure the operating team that, when the SSEPs remain constant, the surgery has not caused additional injury.
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Comparative Study
Thromboelastography and Sonoclot analysis in the healthy parturient.
To compare values for two whole blood viscoelastic coagulation tests, thromboelastography (TEG) and Sonoclot analysis (Sonoclot R Coagulation Analyzer, Sienco, Inc., Morrison, CO), between healthy parturients and nonparturients. ⋯ The differences found in the parturients reflect a hypercoagulable state. If these tests are to be used in evaluating obstetric patients, the results should be compared with values obtained for healthy parturients, not healthy nonparturients.