Acta neurologica Scandinavica
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Acta Neurol. Scand. · Sep 1977
Clinical Trial Controlled Clinical TrialBromocriptine versus placebo in levodopa treated patients with Parkinson's disease.
Twenty patients with idiopathic parkinsonism who had been on optimal levodopa therapy for at least 3 months prior to the investigation and where effect of the treatment was decreasing or side effects were increasing, were treated with bromocriptine in a double-blind crossover trial during a 12 + 12 weeks period. Reduction in disability scores was found significant. ⋯ Doses were 2.5 mg-40 mg. Bromocriptine seems a valuable supplement to previous therapy in these patients.