Acta neurologica Scandinavica
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Acta Neurol. Scand. · Oct 2017
Randomized Controlled TrialRandomized controlled trial of local progesterone vs corticosteroid injection for carpal tunnel syndrome.
A number of studies have demonstrated the neuroprotective effects of progesterone and its influence on the recovery after neural injury. Few studies investigated the efficacy of local progesterone in carpal tunnel syndrome. The objective of this study was to compare the long-term effects of progesterone vs corticosteroid local injections in patients with mild and moderate carpal tunnel syndrome. ⋯ The efficacy of progesterone local injection in mild and moderate CTS is equal and somehow superior to corticosteroid injection for relieving symptoms and improving functional and electrophysiologic findings at long-term follow-up.