Acta cirúrgica brasileira
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Acta cirúrgica brasileira · Jul 2018
NF-kB mediated CX3CL1 activation in the dorsal root ganglion contributes to the maintenance of neuropathic pain induced in adult male Sprague Dawley rats1.
To evaluate the role of CX3CL1 and NF-κB in the lumbar disc herniation induced neuropathic pain. ⋯ CX3XL1 could regulate LDH-induced neuropathic pain through NF-κB pathway. Targeting CX3CL1 and NF-κB may represent a potential treatment for neuropathic pain caused by LDH.