The Annals of pharmacotherapy
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Comparative Study
Atomoxetine ingestions in children: a report from poison centers.
Atomoxetine uses a novel non-stimulant approach to the treatment of attention deficit hyperactivity disorder. There is limited information on overdose of atomoxetine in children or adults. ⋯ In this case series, clinically significant cardiovascular effects requiring direct intervention did not occur. Activated charcoal and/or observation appear to be sufficient for accidental ingestion. Further investigation may be needed to indicate whether seizures occur from atomoxetine ingestion.
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To report a case of sulfhemoglobinemia in a patient receiving phenazopyridine for a urinary tract infection. ⋯ This case of sulfhemoglobinemia, which occurred after the patient took phenazopyridine, is considered a probable adverse event according to the Naranjo probability scale.
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Tramadol is a unique analgesic that has been associated with seizures on overdose. ⋯ Tramadol overdoses frequently cause CNS depression, nausea/vomiting, tachycardia, and seizures. Symptoms generally resolve within 24 hours. Accidental ingestions in children were well tolerated, primarily causing sedation.
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Letter Case Reports
Use of gabapentin for rest pain in chronic critical limb ischemia.
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Review Meta Analysis
Nebulized morphine for relief of dyspnea due to chronic lung disease.
To evaluate the efficacy and safety of nebulized morphine for the management of dyspnea in chronic pulmonary diseases. ⋯ Results from several small studies do not support the use of nebulized morphine for treatment of dyspnea; however, several positive case reports have been published.