American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Oct 1995
Relationship between placental histologic features and umbilical cord blood gases in preterm gestations.
Our purpose was to test the hypothesis that placental histologic lesions reflect abnormal placental respiratory function in preterm gestations. ⋯ Changes in umbilical vein and artery pH, PO2, and PCO2 are significantly related to lesions of uteroplacental vascular pathologic mechanisms and intraplacental thrombosis. Placental lesions may be associated with chronic fetal distress by altering fetal oxygen availability and acid-base status. Placental immaturity resulting from prematurity may be associated with inefficient placental respiratory function and an increased likelihood of cesarean delivery in cases of premature rupture of membranes or preterm labor. Altered fetal acid-base balance plus excess numbers of circulating nucleated erythrocytes suggests that placental respiratory function is functionally abnormal when these lesions are present and leads to fetal tissue hypoxia.
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Am. J. Obstet. Gynecol. · Oct 1995
Randomized Controlled Trial Comparative Study Clinical TrialDoes magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension?
Our purpose was to determine whether seizure prophylaxis with magnesium sulfate prolongs induction of labor in women with pregnancy-associated hypertension. ⋯ Compared with phenytoin, magnesium sulfate seizure prophylaxis in women with pregnancy-associated hypertension does not prolong the induction of labor nor does it result in an increase in cesarean deliveries.
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Am. J. Obstet. Gynecol. · Oct 1995
Randomized Controlled Trial Clinical TrialThe effect of low-dose aspirin on pregnancies complicated by elevated human chorionic gonadotropin levels.
Our purpose was to determine whether elevated second-trimester human chorionic gonadotropin levels identify women likely to benefit from low-dose aspirin therapy. ⋯ Aspirin therapy increased birth weight in all women, especially in women with high human chorionic gonadotropin levels, partly by increasing gestational age at delivery. This observation needs to be confirmed by further studies.
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Am. J. Obstet. Gynecol. · Sep 1995
Randomized Controlled Trial Clinical TrialThe effect of topical 20% benzocaine on pain during loop electrosurgical excision of the cervix.
Our purpose was to evaluate the effect of cervical application of 20% benzocaine on the pain associated with subsequent cervical injection of local anesthetic and tissue excision during the loop electrosurgical excision procedure of the cervix. ⋯ Preoperative cervical application of 20% benzocaine does not appear to reduce the pain associated with either subsequent local anesthetic injection or tissue excision during the loop electrosurgical excision procedure of the cervix.
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Am. J. Obstet. Gynecol. · Sep 1995
Randomized Controlled Trial Clinical TrialPyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial.
Our purpose was to determine the effectiveness of pyridoxine for nausea and vomiting of pregnancy. ⋯ Pyridoxine is effective in relieving the severity of nausea in early pregnancy.