Annals of internal medicine
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The prevalence of osteoporosis is increasing in the United States. ⋯ American College of Physicians. (PROSPERO: CRD42021236220).
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Comment Meta Analysis
Statins increase muscle pain or weakness at 1 y, with an absolute excess of 11 events/1000 person-y.
Cholesterol Treatment Trialists' Collaboration. Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials. Lancet. 2022;400:832-45. 36049498.
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Meta Analysis
Anticoagulant Therapy for Cancer-Associated Thrombosis : A Cost-Effectiveness Analysis.
Direct oral anticoagulants (DOACs) offer an alternative to low-molecular-weight heparin (LMWH) and warfarin for treating cancer-associated thrombosis (CAT). ⋯ None.
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Comment Meta Analysis
In the general population, salt substitutes vs. regular salt reduce BP levels, CV outcomes, and mortality.
Yin X, Rodgers A, Perkovic A, et al. Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis. Heart. 2022;108:1608-15. 35945000.
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Comment Meta Analysis
BP-lowering drugs reduced major CV events by similar amounts in patients with and without type 2 diabetes.
Nazarzadeh M, Bidel Z, Canoy D, et al. Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis. Lancet Diabetes Endocrinol. 2022;10:645-54. 35878651.