Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Nov 2022
Meta AnalysisThe Effect of Orthokeratology Lens on the Axial Length of Globe in Children with Myopia in Asia.
The aim of this meta-analysis was to determine the effect of orthokeratology (OK) lens on the axial length of the eye globe of Asian children with myopia of low and moderate degree compared with children treated with glasses. PubMed, Embase, Web of Science, and Cochrane Library were searched to collect relative researches on the treatment of OK lens in myopia children from January 2000 to July 2021. The authors adopted the standardised mean difference (SMD) as effect size, to estimate the pooled changes of axial length in Asian myopic children. ⋯ According to the follow-up time, the subgroup analysis demonstrated that, SMD = -0.68 (95%CI: -1.43 ~ 0.08, p>0.05) for six months; SMD = -1.00 (95 %CI: -1.38~-0.62, p<0.05) for 12 months; SMD=-0.71 (95%CI: -1.20~-0.21, p<0.05) for two years. In conclusion, in the early treatment, compared with glasses, children with low and moderate myopia wearing OK lenses were more effective in reducing axial elongation in Asia. Key Words: Axial length, Orthokeratology, Myopia, Meta-analysis.