Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jan 2020
Multicenter Study Comparative StudySalivary Biomarker Interleukin-8 Levels in Naswar Users and Non-users.
Salivary biomarkers can be used as diagnostic and predictive aids in early detection of oral cancer or potentially malignant disorders. A cross-sectional comparative study was conducted over a period of one year from August 2016 to August 2017 in a multicentre setting in Islamabad. A total of 60 patients were recruited and divided into two equal groups of naswar users and non-users. ⋯ The results were then analysed by using independent t-test. Statistically significant difference was found regarding the levels of salivary IL-8 between the naswar users and non-users (p <0.001). The levels of salivary IL-8 in non-users were 33.39 ±22.44 pg/ml, while the increased levels of salivary IL-8 in naswar users were found to be 173.48 ±46.52 pg/ml.
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J Coll Physicians Surg Pak · Dec 2019
Multicenter StudyAmino Acid Mutations in NS5B Protein among Treatment-naive Genotype 3A Infected Patients.
To determine the frequency of mutations at specific amino acid positions in full length NS5B gene among chronic HCV genotype 3a infected patients of Peshawar, who had not taken any previous treatment. ⋯ This study reports mutations based on complete NS5B protein of HCV 3a genome that could help predict treatment response among the chronically infected with HCV genotype 3a patients of Peshawar.
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J Coll Physicians Surg Pak · Apr 2015
Multicenter Study Observational StudyHospital-based cancer profile at the Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, pakistan.
To determine a frequency distribution of the type and clinical profile of cancer cases registered at the Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC). ⋯ Hospital-based results obtained from various oncology hospital and departments, can be considered as an effective way forward in getting a preview of cancer burden in the region.
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J Coll Physicians Surg Pak · Nov 2011
Multicenter Study Comparative StudyFactors associated with tobacco smoking among 6-10 grade school students in an urban Taluka of Sindh.
To determine the factors related to tobacco smoking among students of grade 6-10 in an urban setting in Sindh, Pakistan. ⋯ High frequency of tobacco smoking, the attitude toward tobacco consumption and a very high consumption of Areca nuts and other chewable tobacco products by the children warrants urgent action in order to control the tobacco epidemic in Pakistan.