Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Mar 2022
Case ReportsScabies Surrepticius (Bullous Scabies) Presenting as Bullous Impetigo in a Child.
Bullous scabies (BS) is a rare and atypical presentation of scabies, usually affecting elderly males during the seventh decade of life. BS is characterised by intense pruritic eruptions, nocturnal itch, and characteristic blisters with or without burrows in scabies-prone areas. The scabies lesions might predispose patients to bacterial super-infections, resulting in bullae formation similar to bullous impetigo. ⋯ We, herein, report a case of BS in an eight-year boy from Pakistan, treated successfully with 5% topical permethrin and 2% mupirocin. Complete healing was noted within four weeks with no recurrence at two months follow-up. Key Words: Scabies, Bullous, Child, Diagnosis, Treatment.
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J Coll Physicians Surg Pak · Mar 2022
Modulation of Oral Microflora during Helicobacter Pylori Eradication.
To analyse the saliva microbial abundance and composition by 16s rRNA sequence during Helicobacter pylori (H.pylori) eradication. ⋯ The diversity and richness of salivary microbiome were reduced in H.pylori-positive patient, and bismuth-containing quadruple therapy affected oral microbiota. Key Words: Helicobacter pylori, Saliva, Microbiota, RNA, Bismuth.
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J Coll Physicians Surg Pak · Mar 2022
Relationships among Immune Score, TCF21 Methylation, Risk-factor Level, and Prognosis in Prostate Cancer.
To determine whether the immune score and methylation levels of transcription factor 21 (TCF21) could be used as independent diagnostic indicators and prognostic predictors in prostate cancer (PCA). ⋯ The immune score and TCF21 methylation could be used as independent indicators for the diagnosis and prognosis of PCA. Key Words: Prostatic neoplasms, Immunity cellular, DNA methylation.
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J Coll Physicians Surg Pak · Mar 2022
Rise in Child and Adolescent Emergency Psychiatric Presentations: Is it an Evolving Challenge for Mental Health Professionals?
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J Coll Physicians Surg Pak · Feb 2022
Meta AnalysisAssociation between Insulin Resistance and Cognitive Impairment.
The objective of the review was to assess the relationship between insulin resistance and cognitive impairment. Medline, Embase, Web of Science and Cochrane Library were searched. Two independent authors selected studies and extracted data. ⋯ The article showed a negative association between insulin resistance and cognition (R = - 0.262; 95% CI-0.309, - 0.215). There is evidence that insulin resistance may be a mechanism of cognitive impairment. Key Words: Insulin resistance, Insulin, Cognition, Cognitive impairment, Systematic review, Alzheimer's disease.