Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jul 2021
Characteristics of Patients Presenting with COVID-19 from Balochistan Province and Lessons Learnt.
With the spread of COVID-19 in Pakistan, Balochistan province with its unique problems of lowest literacy rates in the country, limited resources and a flail health care system is reporting an increasing number of cases of COVID-19. This study discusses the epidemiological and clinical characteristics of COVID-19 patients from the Balochistan province. ⋯ COVID-19 cases and case fatality ratio is low in Balochistan. Whether this is due to inability to carry out more tests is still to be ascertained. Males and elderly are more affected and fatalities were higher in cases with co-morbid conditions. Balochistan having a weak healthcare system and with the majority of cases being asymptomatic, needs more stringent actions to practice social distancing to avoid further spread of COVID-19.
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J Coll Physicians Surg Pak · Jul 2021
Investigation of Hereditary Cancer Predisposition Genes of Patients with Colorectal Cancer: Single-centre Experience.
To investigate the genetic causes of colorectal cancers (CRCs); and to determine the genotype-phenotype correlation. ⋯ Genes that may cause susceptibility to cancer may play a role in the etiopathogenesis of the CRC. NGS-based multigene panels allow these genes to be detected in the patient and to identify an inherited cancer syndrome. Key Words: Colorectal cancer, Lynch syndrome, Hereditary cancer, Gene, Next generation sequencing.
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J Coll Physicians Surg Pak · Jul 2021
Prealbumin: A New Biomarker for Predicting Prognosis in Patients with Severe COVID-19.
To analyse whether prealbumin could be a new biomarker for predicting mortality in severe COVID-19 patients. ⋯ As a result of this study, it was found that patients with lower levels of prealbumin at the time of admission to the ICU have a higher risk for mortality. It was showed that prealbumin can be a useful biomarker for predicting mortality in patients with severe COVID-19. Key Words: Prealbumin, COVID-19, Mortality, Prognostic biomarkers, Severe disease.
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J Coll Physicians Surg Pak · Jul 2021
Case ReportsChallenges in the Management of Multiple Splenic Abscesses caused by Extensively Drug-resistant (XDR) Salmonella Typhi.
Extensively drug-resistant (XDR) typhoid emerged in Hyderabad, Pakistan in 2016. It spread regionally and globally due to fast travelling. An immuno-competent young male referred by general practitioner, was diagnosed and managed as XDR salmonella typhi with multiple splenic abscesses. ⋯ There is no data on treatment duration and choice between two sensitive antibiotics or both in combination. In the present situation, sensitisation of clinicians to salmonella drug resistance, rational use of antibiotics and prompt public health awareness is the need of the day, especially in endemic areas. KEY WORDS: Extensively drug-resistant (XDR) typhoid,Splenic abscesses, Azithromycin, Meropenem.
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J Coll Physicians Surg Pak · Jul 2021
Case ReportsCan COVID-19 Cause Pancreatitis? A Rare Complication of SARS-CoV-2 Infection.
Coronavirus disease-2019 (COVID-19) emerged as a cluster of atypical pneumonia in Wuhan, China in December 2019. This disease has been declared a pandemic by the World Health Organization. ⋯ Acute pancreatitis is one of the common causes of upper abdominal pain, caused by alcohol consumption, gall stones and various viruses and drugs. We present a case of a young female, who was recently diagnosed as COVID-19 and later on developed acute pancreatitis without any other risk factors. Key Words: COVID-19, SARS-CoV-2, Acute pancreatitis.