Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Mar 2020
Observational StudyPrediction of Lymph Node Metastasis in Colon Cancer via Platelet to Lymphocyte Ratio and Platelet Count.
To investigate the value of preoperative blood tests in predicting lymph node metastasis in colon cancer patients undergoing surgery. ⋯ The platelet counts and PLR values are important in predicting lymph node metastasis in colon cancer, preoperatively. Platelet and PLR values may be more specific and sensitive in predicting preoperative lymph node metastasis in colon cancer patients.
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J Coll Physicians Surg Pak · Mar 2020
Are Lipoprotein Levels and Ratios Able to Predict Mortality due to Sepsis?
To compare lipoprotein levels, and non-HDL to high-density lipoprotein (HDL) ratios of survivors and nonsurvivors of sepsis, and to determine the predictivity levels of specified parameters in mortality. ⋯ Non-HDL to HDL ratio may be used as a useful tool for predicting sepsis mortality. These values may also be included as a part of scoring systems. Further investigations are needed to clarify the role of lipoproteins in sepsis.
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J Coll Physicians Surg Pak · Mar 2020
Changes and Significance of Serum sB7-H3 and Cytokines in Children with Mycoplasma pneumonae Pneumonia.
To explore the relationship between serum sB7-H3 and cytokines (TNF-α, IL-1β and IL-6) and to evaluate the development of Mycoplasma pneumonae pneumonia (MPP) through analysis of the expression levels of above indices in serum of children with MPP. ⋯ Detection of SB7-H3, TNF-α, IL-1β and IL-6 levels may be conducive to early diagnosis of MPP and the judgement of the severity of this disease.
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J Coll Physicians Surg Pak · Mar 2020
Effect of Erythropoiesis Stimulating Agents on Clinical Outcomes in Breast Cancer Patients: A Systematic Review of Randomised Controlled Trials.
The impact of erythropoiesis stimulating agents (ESAs) on clinical outcomes among breast cancer patients is debatable. Current review is aimed to ascertain the efficacy of ESAs among breast cancer patients. Randomised controlled trials (RCTs) were electronically searched. ⋯ Erythropoietin reported no mortality, TEEs, serious ADRs and tumor progression. About 9% patients required transfusions during ESA therapy. Current evidence suggests that use of ESA reduces transfusion need but increases mortality and risks of TEEs.