Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Aug 2015
Observational StudyMolecular Distribution of Deafness Loci in Various Ethnic Groups of the Punjab, Pakistan.
To determine the existence of autosomal recessive deafness loci in different ethnic tribes of the Punjab. ⋯ The genotyping results revealed that DFNB12 locus was the most common followed by DFNB8/10 locus, while the Loci DFNB29, DFNB36 and DFNB37 were less common.
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J Coll Physicians Surg Pak · Aug 2015
Comparative StudyComparison of the Therapeutic Effects of Thymoquinone and Methotrexate on Renal Injury in Pristane Induced Arthritis in Rats.
To determine the effect of thymoquinone and methotrexate on blood urea and serum creatinine in arthritic rats. ⋯ Evaluation of results supported the beneficial effects of thymoquinone in renal injury produced by rheumatoid arthritis.
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J Coll Physicians Surg Pak · Jul 2015
Comparative StudyComparison of Opinion Referendum of Medical and Dental Postgraduates Towards Plagiarism in Bhopal - Central India.
To evaluate awareness and attitude towards plagiarism of postgraduates of health fraternity in Bhopal, Central India. ⋯ Overall plagiarism was favored more by dental students as compared to medical students. Moreover, inadequate level of knowledge and awareness was observed in both the streams. Efforts should be undertaken to motivate health professionals to instill honest behavior in order to preserve the intellectual property right.
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J Coll Physicians Surg Pak · Jul 2015
Association of Physical Exercise on Anxiety and Depression Amongst Adults.
This study was done to determine the frequency of anxiety, depression among those who exercise regularly and those who do not. Across-sectional study was conducted at different gymnasiums of Karachi in July-August 2013. A total 269 individual's ages were 18 - 45 years completed a self-administered questionnaire to assess the data using simple descriptive statistics. ⋯ Chi-square test showed association between anxiety levels and exercise was significantly increased in non-exercisers compared to regular exercisers found to be significant (p=0.015). Individuals who performed regular exercise had a lower frequency of depression (28.9%) than non-exercisers (41.8%). Physical exercise was significantly associated with lower anxiety and depression frequency amongst the studied adult population.
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J Coll Physicians Surg Pak · Jul 2015
Association of Anti-Emetic Efficacy of Ondansetron with G2677T Polymorphism in a Drug Transporter Gene ABCB1 in Pakistani Population.
To determine the association of ABCB1 polymorphism G2677T with anti-emetic efficacy in patients treated with ondansetron for preventing postoperative nausea and vomiting. ⋯ Polymorphism of ABCB1 has an association with responsiveness for ondansetron. There is a role for genetics in the management of PONV.