Saudi Med J
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Randomized Controlled Trial
Comparison of analgesic activity of the addition to neostigmine and fentanyl to bupivacaine in postoperative epidural analgesia.
To compare the analgesic and side effects of bupivacaine in combinations with neostigmine and fentanyl using patient-controlled-epidural analgesia (PCEA) methods in the postoperative period after abdominal hysterectomy. ⋯ Fentanyl and neostigmine by the PCEA method can be used safely for postoperative analgesia after gynecologic surgery. They increase analgesia quality and satisfaction without an increase in side effects.
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Randomized Controlled Trial
Effects of different bolus doses of remifentanil on laryngeal mask airway insertion during day-case surgery.
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To determine the value of known prognostic factors for metastasis in breast cancer by accounting for patient-specific effect of patients who received surgical treatment followed by adjuvant treatment using the frailty model. ⋯ Known risk factors describe the risk of metastasis partly and other unknown or unmeasured factors, such as genetics or environmental factors are important to describe the risk of metastasis in breast cancer.
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Although post-dates is among the most common indications for induction of labor, no studies have identified the predictors of cesarean section (C/S) in that population. The high cesarean rate in our institution for this group of women triggered us to assess different induction practices to elicit potential causes. ⋯ The need for oxytocin or less than 2 doses of PG is associated with increased risk of C/S. Whether oxytocin was given according to protocol (ideally) or not, made no difference to the C/S risk in this population.
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To compare the inotropic and chronotropic effects of ropivacaine and bupivacaine in an isolated, spontaneously beating rat heart, and to determine the reversal effects of dopexamine on these effects. ⋯ Bupivacaine had more depressant effects on cardiac contractility and chronotropy than ropivacaine. Dopexamine may provide an alternative to presently recommended pharmacological therapy in cases of bupivacaine and ropivacaine induced cardiotoxicity. But, the clinical impact of the use of dopexamine in this situation deserves further evaluation.