Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
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Zhonghua Jie He He Hu Xi Za Zhi · Feb 2002
[Correlation of angiogenesis with expression of vascular endothelial growth factor and its receptors in lung carcinoma].
In order to search new therapeutic strategies, study the relationship between angiogenesis and vascular endothelial growth factor and its two receptors in lung carcinoma. ⋯ (1) Not or rarely affected by clinical factors, MVD is a good and independent prognostic factor for patients with lung carcinoma. (2) The angiogenesis is induced not only by VEGF itself, but via VEGF receptors too. VEGF and its receptors thus appear to be new therapeutic targets for lung carcinoma. (3) VEGF appears to be produced by both tumor cells and stromal fibroblasts. (4) The result suggests that tumor expansion and angiogenesis are mainly induced by an autocrine pathway and a paracrine loop of VEGF via KDR.
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Zhonghua Jie He He Hu Xi Za Zhi · Nov 2001
Controlled Clinical Trial[The effects of long-term domiciliary oxygen therapy on patients of chronic obstructive pulmonary disease with hypoxaemia].
To observe the effects of long-term domiciliary oxygen therapy (LTDOT) on patients of chronic obstructive pulmonary disease (COPD) with hypoxaemia. ⋯ Long-term domiciliary oxygen therapy could reduce the load of the right heart, improve the patients's psychological status and quality of life.
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Zhonghua Jie He He Hu Xi Za Zhi · Nov 2001
[Pulmonary surfactant impairment in the development of ventilator-induced lung injury in rats].
To evaluate whether pulmonary surfactant (PS) impairment plays a role in the development of ventilator-induced lung injury (VILI). ⋯ A short period of mechanical ventilation with high PIP alone can cause VILI in rats that is associated with PS impairment; both exogenous PS and PEEP can restore or preserve alveolar space PS composition and function, attenuate abnormalities of lung oxygenation and mechanics, indicating PS impairment may play an important role in the development of VILI.
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Zhonghua Jie He He Hu Xi Za Zhi · Nov 2001
[Effects of aspiration of airway dead space on blood gases and respiratory mechanics in acute hypercapnia model dogs].
To establish the method of aspiration of airway dead space (ASPIDS) and evaluate the effects of ASPIDS on elimination of CO2 and improvement of ventilation efficiency. ⋯ The ASPIDS device is a simple and practical adjunct method to mechanical ventilation, it can more effectively decrease PaCO2 than TGI, and maintain lower airway pressure.
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Zhonghua Jie He He Hu Xi Za Zhi · Oct 2001
[Changes of pulmonary function and partial oxygen pressure before and after bronchoalveolar lavage in patients with interstitial lung diseases].
To study the influence of bronchoalveolar lavage(BAL) on pulmonary physiological function and partial oxygen pressure(PaO2). ⋯ Pulmonary physiological function and partial oxygen pressure of patients with ILD are influenced by BAL process.