NeuroImage. Clinical
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NeuroImage. Clinical · Jan 2018
Randomized Controlled TrialEnhancing treatment of osteoarthritis knee pain by boosting expectancy: A functional neuroimaging study.
Expectation can significantly modulate pain and treatment effects. This study aims to investigate if boosting patients' expectancy can enhance the treatment of knee osteoarthritis (KOA), and its underlying brain mechanism. ⋯ Our study provides a novel method and mechanism for boosting the treatment of pain in patients with KOA. Our findings may shed light on enhancing outcomes of pharmacological and integrative medicines in clinical settings.