Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
-
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Jul 2013
[Correlation between the numbers of peripheral blood dendritic cells and the clinical manifestations in children with respiratory syncytial virus bronchiolitis].
To detect the quantity of peripheral blood myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs) in children with bronchiolitis infected by respiratory syncytial virus (RSV) and analyze the correlation with the severity of the disease. ⋯ The number of mDCs in peripheral blood of the children with RSV bronchiolitis significantly increased at the early stage, and in contrast pDCs were reduced. The increased number of mDCs indicates that the clinical manifestations are slighter, and the decreased number of pDCs suggests more wheezing of the children.
-
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Mar 2013
[Mechanism of hematopoietic stem/progenitor cell aging induced by radiation damage].
To explore the mechanism underlying the aging of hematopoietic stem/progenitor cells (HSC/HPC) induced by radiation stress. ⋯ DNA damage and senescence-associated biological changes of Sca-1(+);HSC/HPC can be achieved by X-ray radiation, which may be involved in p16(INK4a);-Rb and p19(Arf);-p53-p21(Cip1/Waf1); signal pathways.
-
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Jan 2013
[Low-intensity pulsed ultrasound stimulates the extracellular matrix synthesis of human degenerative nucleus pulposus cells via activating PI3K/Akt pathway].
To investigate the effect of low-intensity pulsed ultrasound (LIPUS) on the extracellular matrix synthesis of human degenerative nucleus pulposus cells and explore the underlying mechanism. ⋯ The LIPUS can stimulate the extracellular matrix synthesis of degenerative human nucleus pulposus cells cultured in calcium alginate beads via activating PI3K/Akt pathway.
-
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Sep 2012
[Protective effect of lipoxin A4 against rhabdomyolysis-induced acute kidney injury in rats].
To investigate the protective effect of lipoxin A4 (LXA(4);) against rhabdomyolysis-induced acute kidney injury (AKI) and the possible mechanism. ⋯ LXA(4); can significantly protect rats against AKI partly by blocking NF-κB activation and reducing inflammatory cytokine expression and inflammatory cells infiltration in the kidney.
-
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Apr 2012
[Changes and the clinical significance of CD4⁺ CD25⁺ regulatory T cells and Th17 cells in peripheral blood of infants with respiratory syncytial virus bronchiolitis].
To observe the percentages of CD4(+);CD25(+); regulatory T cells (Tregs) and Th17 cells and the levels of IL-10, TGF-β and IL-17 in peripheral blood of infants with respiratory syncytial virus (RSV) bronchiolitis. The relationship between above cells, cytokines and RSV bronchiolitis was determined. ⋯ The imbalance between Tregs and Th17 cells in peripheral blood of infants with RSV bronchiolitis may be one of the pathogenesis of RSV bronchiolitis.