Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
-
Randomized Controlled Trial
Preserved somatosensory conduction in complete spinal cord injury: Discomplete SCI.
Spinal cord injury (SCI) disrupts the communication between brain and body parts innervated from below-injury spinal segments, but rarely results in complete anatomical transection of the spinal cord. The aim of this study was to investigate residual somatosensory conduction in clinically complete SCI, to corroborate the concept of sensory discomplete SCI. ⋯ Identifying patients with residual somatosensory connections might open the door for new rehabilitative and restorative strategies as well as inform research on SCI-related conditions such as neuropathic pain and spasticity.
-
Delirium is associated with increased electroencephalography (EEG) delta activity, decreased connectivity strength and decreased network integration. To improve our understanding of development of delirium, we studied whether non-delirious individuals with a predisposition for delirium also show these EEG abnormalities. ⋯ Predisposition for delirium is not consistently related to EEG characteristics that can be found during delirium.
-
To evaluate intraoperative use of a novel high-density circular grid in detecting after-discharges (AD) on electrocorticography (ECoG) during functional brain mapping (FBM). ⋯ Circular grids offer high-resolution ECoG during intraoperative FBM for detection of ADs.
-
Transcranial direct current stimulation (tDCS) is a neuromodulation scheme that delivers a small current via electrodes placed on the scalp. The target is generally assumed to be under the electrode, but deep brain regions could also be involved due to the large current spread between the electrodes. This study aims to computationally evaluate if group-level hotspots exist in deep brain regions for different electrode montages. ⋯ The presented EF atlas in deep brain regions can be used to explain tDCS mechanism or select the most appropriate tDCS montage.
-
Patients with Parkinson's disease (PD) have deficits in lower-limb functions such as gait, which involves both cognitive and motor dysfunction. In PD, theta and beta brain rhythms are associated with cognitive and motor functions, respectively. We tested the hypothesis that PD patients with lower-limb abnormalities would exhibit abnormal theta and beta rhythms in the mid-frontal cortical region during lower-limb action. ⋯ These data provide insight into mechanisms of lower-limb dysfunction in PD with FOG.