Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Multicenter Study
Reliability in the assessment of paediatric somatosensory evoked potentials post cardiac arrest.
To measure inter- and intra-rater agreement in the interpretation of cortical somatosensory evoked potential (SSEP) components following paediatric cardiac arrest (CA) in multi-professional neurophysiology teams. ⋯ Clinicians using SSEPs in the intensive care unit should be aware of the inter-rater variability when interpreting SSEPs as absent.
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Randomized Controlled Trial Multicenter Study
In pursuit of a sensitive EEG functional connectivity outcome measure for clinical trials in Alzheimer's disease.
In clinical trials in Alzheimer's Disease (AD), an improvement of impaired functional connectivity (FC) could provide biological support for the potential efficacy of the drug. Electroencephalography (EEG) analysis of the SAPHIR-trial showed a treatment induced improvement of global relative theta power but not of FC measured by the phase lag index (PLI). We compared the PLI with the amplitude envelope correlation with leakage correction (AEC-c), a presumably more sensitive FC measure. ⋯ AEC-c may be a robust and sensitive FC measure for detecting treatment effects.
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Multicenter Study
Propofol does not affect the reliability of early EEG for outcome prediction of comatose patients after cardiac arrest.
To quantify the effects of propofol on the EEG after cardiac arrest and to assess their influence on predictions of outcome. ⋯ We confirm the reliability of EEG-based outcome predictions in propofol-sedated patients after cardiac arrest.
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Randomized Controlled Trial Multicenter Study Observational Study
Time to epileptiform activity and EEG background recovery are independent predictors after cardiac arrest.
Investigate the temporal development of EEG and prognosis. ⋯ Patients with early background recovery combined with late appearance of epileptiform activity may have a good outcome.
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Multicenter Study Observational Study
Changes in electrocorticographic beta frequency components precede spreading depolarization in patients with acute brain injury.
Spreading depolarization (SD) occurs after traumatic brain injury, subarachnoid hemorrhage, malignant hemispheric stroke and intracranial hemorrhage. SD has been associated with secondary brain injury, which can be reduced by ketamine. In this present study frequency bands of electrocorticographic (ECoG) recordings were investigated with regards to SDs. ⋯ Alteration of beta frequency might help to predict occurrence of SDs in acutely brain injured patients.