Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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The Hurst exponent (HE) is a nonlinear method measuring the smoothness of a fractal time series. In this study we applied the HE index, extracted from electroencephalographic (EEG) recordings, as a measure of anesthetic drug effects on brain activity. ⋯ The HEOLFB could be used as an index for accurately estimating the effect of anesthesia on brain activity.
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This study examined whether attention deficits in fragile X syndrome (FXS) can be traced back to abnormalities in basic information processing. ⋯ These findings demonstrate that auditory information processing in FXS males is critically impaired relative to visual information processing.
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Controlled Clinical Trial
Evoked potentials and quantitative thermal testing in spinal cord injury patients with chronic neuropathic pain.
Neuropathic pain (NP) is a common symptom following spinal cord injury (SCI). NP may be associated with altered processing of somatosensory pathways in dermatomes rostral to the injury level. To explore this possibility, the characteristics of contact heat evoked potentials (CHEPs) and quantitative thermal testing (QTT) were studied at and above the lesion level in SCI patients with NP. The goal was to determine processing abnormalities correlated with data from clinical evaluations. ⋯ SCI somatosensory processing alteration may contribute to the understanding of the mechanisms underlying NP and secondary changes to NP in SCI.
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Controlled Clinical Trial
Reorganization of multi-muscle and joint withdrawal reflex during arm movements in post-stroke hemiparetic patients.
To investigate the behavior of the nociceptive withdrawal reflex (NWR) in the upper limb during reaching and grasping movements in post-stroke hemiparetic patients. ⋯ The central nervous system is unable to use the NWR substrate dynamically and flexibly in order to select the muscle synergies needed to govern the spatio-temporal interaction among joints.
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Clinical Trial
Tonic pain and continuous EEG: prediction of subjective pain perception by alpha-1 power during stimulation and at rest.
Pain neurophysiology has been chiefly characterized via event-related potentials (ERPs), which are exerted using brief, phase-locked noxious stimuli. Striving for objectively characterizing clinical pain states using more natural, prolonged stimuli, tonic pain has been recently associated with the individual peak frequency of alpha oscillations. This finding encouraged us to explore whether alpha power, reflecting the magnitude of the synchronized activity within this frequency range, will demonstrate a corresponding relationship with subjective perception of tonic pain. ⋯ The relevance of alpha-1 power to tonic pain perception may deepen the understanding of the mechanisms underlying the processing of prolonged noxious stimulation.