African health sciences
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African health sciences · Mar 2022
Multicenter StudyA comparative analysis on risk of pulmonary hypertension in children with Atrio-ventricular (AV) canal defect: a multi-centre study.
This study is aimed at determining the risk of pulmonary hypertension in children with AV canal defect when compared with children with other congenital heart disease. ⋯ Majority of children with AV canal defect presented with pulmonary hypertension. These children present with higher odds of having pulmonary hypertension and clinical symptoms than children with other types of congenital heart disease.
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African health sciences · Mar 2021
Multicenter StudyCharacteristics and outcomes of patients with multiple myeloma at the Uganda Cancer Institute.
Data on multiple myeloma (MM) in sub-Sahara Africa is scarce. In Uganda, there is a progressively increasing incidence of MM over the years. ⋯ Most patients with multiple myeloma at the UCI were diagnosed at a relatively young age, presented with late stage disease and bone pain, and had a shorter survival time. Factors associated with worse survival were Durie-Salmon stage III and LDH >225 U/L.
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African health sciences · Dec 2020
Multicenter Study Observational StudyAntibiotic prescribing practices in three neonatology units in Kigali, Rwanda. - an observational study.
There is limited published data on antibiotic use in neonatal units in resource-poor settings. ⋯ The median antibiotic duration for neonates with normal lab results exceeded the recommended duration mandated by the national neonatal protocol. We recommend the development of antibiotic stewardship programs in neonatal units in Rwanda to prevent the adverse effects which may be caused by inappropriate or excessive use of antibiotics.
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African health sciences · Dec 2018
Multicenter StudyEvaluation of antibiotic prescriptions and use in under-five children in Ibadan, SouthWestern Nigeria.
Irrational antibiotic prescriptions for children is a global concern requiring periodic evaluation and monitoring. ⋯ Antibiotic prescriptions for under-fives was largely based on symptoms indicative of bacterial infections, thereby corroborating the widespread empirical antibiotic prescribing. Considerable number of mothers engaged in self-recommendation of antibiotics for their under-fives. Thus, there is a need for continuous enlightenment of prescribers and mothers on rational use of antibiotics, while microbiological confirmation of clinical diagnosis is encouraged for evidence-based antibiotic prescribing.
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African health sciences · Jun 2014
Multicenter StudyStroke prevalence amongst sickle cell disease patients in Nigeria: a multi-centre study.
Stroke is a life-changing, debilitating complication of sickle cell disease (SCD). Previous studies had recorded high stroke prevalence amongst this group of patients. Nigeria has a large population of people affected by this condition and this study aims to assess the stroke prevalence in this large population. ⋯ The stroke prevalence in Nigeria is lower than previously recorded rates and further studies will be required to investigate other factors which may play a role.