Annals of internal medicine
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Comment Meta Analysis
BP-lowering drugs reduced major CV events by similar amounts in patients with and without type 2 diabetes.
Nazarzadeh M, Bidel Z, Canoy D, et al. Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis. Lancet Diabetes Endocrinol. 2022;10:645-54. 35878651.
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Review Case Reports Meta Analysis
The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population : A Systematic Review and Dose-Response Meta-analysis.
To what extent the COVID-19 pandemic and its containment measures influenced mental health in the general population is still unclear. ⋯ Swiss National Science Foundation. (PROSPERO: CRD42020180049).
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Review Meta Analysis
Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain : A Systematic Review and Meta-analysis.
The comparative benefits and harms of opioids for musculoskeletal pain in the emergency department (ED) are uncertain. ⋯ None. (PROSPERO: CRD42021275293).
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The effectiveness of screening for colorectal cancer (CRC) by sex and age in randomized trials is uncertain. ⋯ Health Fund of South-East Norway.
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Comment Meta Analysis
In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding.
Kurlander JE, Barnes GD, Fisher A, et al. Association of antisecretory drugs with upper gastrointestinal bleeding in patients using oral anticoagulants: a systematic review and meta-analysis. Am J Med. 2022;135:1231-43.e8. 35679879.