Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Feb 2023
Review Meta AnalysisComparison of Contrast-enhanced versus Non-enhanced Helical Computed Tomography in the Diagnosis of Acute Appendicitis: A Meta-analysis.
The aim of this review was to compare the performance of contrast-enhanced versus non-contrast-enhanced helical computed tomography (CT) for acute appendicitis as reported. A systematic search of PubMed and Embase was conducted. The sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the summary receiver operating characteristic curves (AUC) were evaluated using Meta-DiSc. ⋯ The AUC was not statistically different (Z=0.737, p=0.461). This data suggest that the contrast-enhanced CT has better diagnostic performance for acute appendicitis than non-contrast CT. Key Words: Acute appendicitis, Contrast-enhanced computed tomography' scan, Non-contrast-enhanced computed tomography' scan, Meta-analysis.
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J Coll Physicians Surg Pak · Feb 2023
Observational StudySecondary Infections in Critical Patients with COVID-19 Associated ARDS in the ICU: Frequency, Microbiologic Characteristics and Risk Factors.
To determine frequency, microbiologic characteristics and risks of secondary infections in patients with Coronavirus disease 2019 (COVID-19) associated acute respiratory distress syndrome (ARDS). ⋯ SARS-CoV-2, COVID-19, Acute respiratory distress syndrome, Secondary infections.
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J Coll Physicians Surg Pak · Feb 2023
Do Stoma Formation and Use of Vacuum Assisted Closure System Affect Mortality in Perineal Fournier's Gangrene?
The aim of this study was to identify the effects of creation of stoma and the use of vacuum-assisted closure systems on postoperative mortality and hospital stay in patients with Fournier's gangrene involving anorectal region. ⋯ Fournier's gangrene, Vacuum-assisted closure system, Stoma, Anorectal region, Perineum, Mortality.
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J Coll Physicians Surg Pak · Feb 2023
Observational StudyThe Role of YAP-JNK in the Mitophagy, Migration, and Invasion of Gastric Cancer.
To determine the function of the YAP-JNK-mitophagy signalling pathway in gastric cancer (GC). ⋯ Gastric cancer, YAP, JNK, Autophagy.