Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Jun 2022
Meta AnalysisNeoadjuvant Immune Checkpoint Inhibitors in Non-small Cell Lung Cancer.
Lung cancer is the leading cause of cancer-related death worldwide. A meta-analysis was conducted to assess the benefits and risks of neoadjuvant immune checkpoint inhibitors (ICIs) in non-small cell lung cancer (NSCLC). Online databases, including PubMed, Embase, Web of Science, Cochrane Library, and clinicaltrials.gov, were retrospectively and systematically searched for eligible trials from database inception to May 2021. ⋯ In terms of safety, the pooled rate of any-grade and grade 3-5 treatment-related adverse effects (TRAEs) were 57% (95% CI 38-76%) and 15% (95% CI 6-28%). Eventually, the study concludes that neoadjuvant ICIs are effective and safe for patients with early-stage NSCLC. Key Words: Neoadjuvant therapy, Immune checkpoint inhibitors, Non-small cell lung cancer, Meta-analysis.
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J Coll Physicians Surg Pak · Jun 2022
Observational StudyDiagnostic Value of Preoperative Haemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score in Predicting Tumour Budding in Colorectal Cancer.
To investigate the value of preoperative haemoglobin, albumin, lymphocyte, and platelet (HALP) score in predicting tumour budding in colorectal carcinoma. ⋯ Colorectal cancer, Tumor, Pathology, Hemoglobin, Albumin.
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J Coll Physicians Surg Pak · Jun 2022
Various Risk Factors of Overweight and Obesity among Children Aged 5-16 Years.
To determine the determinants of overweight and obesity among children aged 5-16 years. ⋯ Children, Obese, Overweight, Risk factors, Pakistan.
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J Coll Physicians Surg Pak · Jun 2022
Comparison of Femoral and Internal Jugular Vein Catheterisation Trends in Sick Infants.
To compare two different ways of central venous access in newborns regarding complications and success rates. ⋯ Femoral vein, Internal jugular vein, Central venous access, Catheter-related infection, Infants.