Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
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J Coll Physicians Surg Pak · Oct 2017
ReviewReview Typology: The Basic Types of Reviews for Synthesizing Evidence for the Purpose of Knowledge Translation.
With advances in medical practice and fields of research, reviews occupy a key position for summarizing existing knowledge. Due to the differences and overlap in terminology, the full potential for reviews may be lost due to confusion of indistinct approaches. The main objective of this study was to provide a descriptive outline of each of the common review types with their characteristics and examples in a health care system. ⋯ Nine common types of reviews and associated methodologies were evaluated against the already established SALSA framework. Their description, strengths and weaknesses are presented. The results provided a basic idea of different types of reviews based on the intended level of knowledge synthesis by which researchers can identify the appropriate type of review based on their intended audience.
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J Coll Physicians Surg Pak · Oct 2017
Polymorphisms in the Growth Differentiation Factor 5 (GDF 5) Gene in Knee Osteoarthritis.
To identify the frequency of the rs143383 SNPin the GDF5 gene, which is located in the 5'-untranslated region of Turkish population with knee osteoarthritis (OA). ⋯ This study demonstrated that there is a correlation of +104T/C polymorphism in the 5'-UTR of GDF5 with knee OAin a Turkish population.
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J Coll Physicians Surg Pak · Aug 2017
Prognostic Potential of N-Cadherin in Oral Squamous Cell Carcinoma via Immunohistochemical Methods.
To assess the prognostic potential for N-cadherin in oral squamous cell carcinoma and oral epithelial dysplasia. ⋯ N-cadherin can be used as a potential biomarker for early diagnosis of OSCC. However, the N-cadherin expression did not show any correlation with the histological grade of OSCC.
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J Coll Physicians Surg Pak · Aug 2017
Case ReportsAcute Complete Adult-onset Kawasaki Disease in a Middle-Aged Woman.
A 55-year-old Chinese lady was diagnosed with acute complete Kawasaki disease (KD) in January 2015. To our knowledge, this patient was the first described woman who was over 50 years and fulfilled all the characteristics of acute complete KD. The patient had a striking result on the 26th day since this disease onset after the initiation of treatment of immunoglobulin (IG) and aspirin; and did not have any complications up to now. The purpose of this case report was to raise the awareness of KD in the middle-aged persons and the therapeutic schedules, as there is no valid therapeutic therapeutic for adults with KD.