Transversus abdominis plane block with liposomal bupivacaine improved post-caesarean section analgesia when used as part of a multimodal analgesia protocol.
@Doctormatt interestingly, not only is the pressor-sparing & hypotension-reducing benefits of prophylactic ondansetron not seen among elderly or frail patients – but it doesn't even seem to occur outside Caesarean sections! (at least wasn't when I last looked).
Perioperative β-blocker use should be tailored for patient and surgical risk factors, most importantly because of the association with increased mortality and stroke when their use is generalised.
Pre-spinal-anaesthesia administration of IV ondansetron 4 mg reduces the ED50 of prophylactic phenylephrine infusion by 26% among patients undergoing elective Caesarean section.
Daniel Jolley
Matthew Smith