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pearl
1
The Clinical Frailty Scale provides meaningful additional outcome prediction to traditional preoperative risk factors among non-cardiac surgery patients.
McIsaac DI, Harris EP, Hladkowicz E et al. Prospective Comparison of Preoperative Predictive Performance Between 3 Leading Frailty Instruments. Anesth. Analg. 2020 Jul 1; 131 (1): 263-272.
  Daniel Jolley
pearl
1
Remifentanil does not reduce the performance of BIS-based closed-loop propofol anesthesia with a remifentanil effect site concentration of 2.8-7.5 ng/mL.
Neckebroek M, JHL Boldingh, De T et al. Influence of Remifentanil on the Control Performance of the Bispectral Index Controlled Bayesian-Based Closed-Loop System for Propofol Administration. Anesth. Analg. 2020 Jun 1; 130 (6): 1661-1669.
  Daniel Jolley
pearl
1
Pediatric airway management guidelines for COVID-19 patients relies upon non-clinical studies, infectious disease data and expert opinion.
Matava CT, Kovatsis PG, Lee JK et al. Pediatric Airway Management in COVID-19 patients - Consensus Guidelines from the Society for Pediatric Anesthesia's Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society. Anesth. Analg. 2020 Jul 1; 131 (1): 617361-73.
  Daniel Jolley
pearl
1
The analgesic benefit and safety of pre-hospital femoral nerve block compared with other, more common forms of pain-relief remains uncertain.
Raatiniemi L, Magnusson V, Hyldmo PK et al. Femoral nerve blocks for the treatment of acute prehospital pain: a systematic reviewwith meta-analysis. Acta Anaesthesiol Scand. 2020 Sep 1; 64 (8): 1038-1047.
  Daniel Jolley
pearl
1
Neither perioperative aspirin or clonidine show long-term benefit in terms of death, cardiovascular complication, cancer, or chronic pain at 1 year, except for a benefit of aspirin for patients with a history of PCI.
Sessler DI, Conen D, Leslie K et al. One-year Results of a Factorial Randomized Trial of Aspirin versus Placebo and Clonidine versus Placebo in Patients Having Noncardiac Surgery. Anesthesiology. 2020 Apr 1; 132 (4): 692-701.
  Daniel Jolley
pearl
1
Sugammadex showed no benefit over neostigmine when assessed using PACU spirometry, muscle strength, TOFR or other indicators of recovery up to 2 hours post-reversal.
Abola RE, Romeiser J, Rizwan S et al. A randomized-controlled trial of sugammadex versus neostigmine: impact on early postoperative strength. Can J Anaesth. 2020 Aug 1; 67 (8): 959-969.
  Daniel Jolley
pearl
1
Careful planning and preparation before emergency cesarean section for COVID-19 infected parturient is essential to reduce healthcare worker infection and ensure mother & infant safety.
Du Y, Wang L, Wu G et al. Anesthesia and protection in an emergency cesarean section for pregnant woman infected with a novel coronavirus: case report and literature review. J Anesth. 2020 Aug 1; 34 (4): 613-618.
  Daniel Jolley
pearl
1
Neurally-adjusted ventilatory assist improves patient-ventilator synchrony although with uncertain effect on clinical outcome..
Pettenuzzo T, Aoyama H, Englesakis M et al. Effect of Neurally Adjusted Ventilatory Assist on Patient-Ventilator Interaction in Mechanically Ventilated Adults: A Systematic Review and Meta-Analysis. Crit. Care Med. 2019 Jul 1; 47 (7): e602-e609.
  Daniel Jolley
pearl
1
Vitamin B12a (hydroxocobalamin) may be beneficial in managing vasoplegic syndrome following cardiopulmonary bypass.
Armour S, Armour TK, Joppa WR et al. Use of Hydroxocobalamin (Vitamin B12a) in Patients With Vasopressor Refractory Hypotension After Cardiopulmonary Bypass: A Case Series. Anesth. Analg. 2019 Jul 1; 129 (1): e1-e4.
  Daniel Jolley
pearl
1
Within the Fear Avoidance Model of pain, quantitative neurophysiological factors provide additional conceptual benefit when integrated along with traditional psychologically aspects of the FAM.
Uddin Z, Woznowski-Vu A, Flegg D et al. Evaluating the novel added value of neurophysiological pain sensitivity within the Fear-Avoidance Model of Pain. Eur J Pain. 2019 May 1; 23 (5): 957-972.
  Daniel Jolley