Nutrition
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The number of chronic diseases is associated with the reduction in muscle mass and strength in older people (≥60 y of age). The purpose of this study was to asses the association between multimorbidities and handgrip strength in older community-dwelling individuals from a city in southern Brazil, identifying potential differences according to sex and loss of muscle mass. ⋯ Results from the present study indicated an association between manual grip strength and multimorbidity among this population, and the effect measures were greater in men. Manual grip strength proved to be a good marker of health in this population, especially in those who did not present with myopenia.
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The aim of this study was to review the association of dietary intake of oleic and linoleic acids (OA and LA, respectively) with depressive symptoms in perimenopausal women. ⋯ Intake of OA and LA may be positively associated with depressive symptoms in perimenopausal women.
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Lifestyle, obesity, and eating habits are emerging as determinants for the instability of telomeres. The increase in childhood and adolescent obesity and the association of biochemical profiles and dietary components with telomere length (TL) makes it an important issue in nutritional research. The aim of the present study was to investigate TL and its association with ethnic background, adiposity, clinical and biochemical parameters, and dietary patterns among Brazilian children and adolescents. ⋯ The results suggested that both biochemical parameters and the intake of antioxidant-rich food, such as fruits and vegetables, are associated with the stability of telomere biology among young Brazilians.
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The aim of this study was to investigate the association between single-nucleotide polymorphisms (SNPs) in vitamin D metabolic pathway genes, serum 25-hydroxyvitamin D [25(OH)D] concentrations, and leukocyte telomere length (LTL) in Brazilian adults. ⋯ Genetic variations in the gene encoding vitamin D binding protein (GC - rs2282679) were associated with LTL, suggesting an influence of vitamin D status on telomere length that may start early in life.
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Previous studies have demonstrated that nutritional status is associated with non-alcoholic fatty liver disease (NAFLD). Meanwhile, subclinical inflammation is associated with the prevalence of NAFLD. To our knowledge, however, no study has investigated the intermediary effect of inflammation on the association between dietary pattern and NAFLD. Thus, the aim of this case-control study was to explore the intermediary effect of inflammation on the association between dietary patterns and NAFLD. ⋯ The present data suggested that inflammation may mediate the association between dietary patterns and NAFLD.