Dermatologica
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The behaviour of Sarcoptes scabiei var. hominis has been studied in the skin of 2 patients with hyperkeratotic scabies. After examination under the scanning electron microscope, the skin specimens can be reprocessed for light microscopic examination. Original aspects and the dynamics of the burrowing parasite are presented, namely its penetration into the epidermis, the elimination of digestive residues and the maturation of the parasite's eggs.
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This study presents a case of two of the more uncommon side effects of bleomycin therapy for a metastasized testicular carcinoma: Raynaud's phenomenon and acral sclerosis. It is suggested that this association indicates a common pathogenic mechanism. These side effects may serve as an experimental model in the study of Raynaud's phenomenon and acral sclerosis.
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We report the case of a patient suffering from mycosis fungoides and plasma cell myeloma. It is postulated that this is not a fortuitous association, but that the B cell neoplasm evolved under the sustained inducer stimulus of the malignant T lymphocytes. This hypothesis is suggested by the demonstration of the helper phenotype of the cutaneous lymphocytes associated with a predominance of helper lymphocytes in blood.
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A 25-year-old man with solar urticaria is described. The action spectrum ranged from 400 to 500 nm. ⋯ The urticarial reaction was not blocked by local injection of antihistamines and not prevented by histamine depletion with polymyxin B sulfate. These data suggest that histamine may not play a major role in weal production in this case.
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A patient with typical larva migrans lesions associated with a highly pruritic papular folliculitis is presented. The time course of the evolution and the pathological picture - with local accumulation of lymphocytes, mast cells and eosinophils - mirror a typical thymus-dependent reaction to parasitic infestation. The papular and serpiginous lesions did not respond to the same type of therapy.