Articles: respiratory-distress-syndrome.
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The adult respiratory distress syndrome, marked by severe, refractory hypoxemia, noncardiogenic pulmonary edema, and stiff, noncompliant lungs, demands quick recognition and intensive care. This article reviews the disease process and current and experimental treatments for it.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 1997
Randomized Controlled Trial Comparative Study Clinical TrialPulmonary function changes after nebulised and intravenous frusemide in ventilated premature infants.
To compare the effects of a single dose of frusemide administered either intravenously or by nebulisation on pulmonary mechanics in premature infants with evolving chronic lung disease. ⋯ Single dose nebulised frusemide improves pulmonary function in premature infants with evolving chronic lung disease without adverse effects on fluid and electrolyte balance.
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Mayo Clinic proceedings · Jul 1997
Case ReportsOrganizing diffuse alveolar damage associated with progressive systemic sclerosis.
Diffuse alveolar damage (DAD) is a relatively nonspecific pattern of acute lung injury that can be observed in a wide range of clinical circumstances. DAD has often been recognized in association with various connective tissue diseases; however, to our knowledge, it has not been previously reported in the setting of progressive systemic sclerosis. ⋯ Open-lung biopsy specimens from both patients showed a histologic pattern of DAD with no identifiable cause other than their progressive systemic sclerosis. Our results suggest that DAD should be added to the list of pleuropulmonary complications of progressive systemic sclerosis.
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Various strategies have been tested in attempts to improve gas exchange in patients with Acute Respiratory Distress Syndrome (ARDS). However, it appears that the simple non-invasive act of prone positioning of the critically ill ARDS patient may improve gas exchange while preventing potential complications of high positive end expiratory pressure (PEEP), volutrauma, and oxygen toxicity.
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The Journal of pediatrics · Jul 1997
Dose response to inhaled nitric oxide in pediatric patients with pulmonary hypertension and acute respiratory distress syndrome.
To determine the pulmonary vascular functional dose response to inhaled nitric oxide (NO) for infants and children with acute respiratory distress syndrome and pulmonary artery hypertension. ⋯ Inhaled NO appears to be a safe, although variably effective, therapy for the treatment of infants and children with acute respiratory distress syndrome. The maximum dose response occurs between 20 and 40 ppm of inhaled NO. Systemic side effects did not occur in any child who received NO therapy.